Possible genetic influences in familial sarcoidosis
نویسندگان
چکیده
منابع مشابه
Possible genetic influences in familial sarcoidosis.
Five families (three English, one Irish, one West Indian) contained eleven members with sarcoidosis, nine of whom have been investigated and followed. Their multisystem involvement and course was similar to that of other patients attending the Sarcoidosis Clinic at the Royal Northern Hospital. There were three brother-sister and two mother-offspring relations; it was not observed in a father-of...
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BACKGROUND Most non-chromosomal congenital heart defects are thought to be caused by the interaction of genetic factors involving multiple genes and environmental factors. Families that have several affected members have been reported, however, which suggests that a single autosomal dominant or recessive gene may cause the cardiac defects. A family in which atrioventricular septal defect seemed...
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OBJECTIVE To investigate the heritability of memory and other cognitive measures in families with multiple individuals with Alzheimer disease (AD) to determine if neuropsychological measures can be used to better understand genetic contributions to AD. METHODS The genetic contributions to the variation in declarative memory, attention, abstract reasoning, language, and visuospatial function u...
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Sarcoidosis uncommonly presents with bronchial narrowing, produced by mucosal lesions or external compression by enlarged glands. We report two sisters with sarcoidosis who presented with severe inspiratory stridor as a result of obstruction of the major airways. An unusual feature of the second case was unilateral glandular enlargement. This produced such severe obstruction that mechanical dil...
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Introduction Sarcoidosis is a systemic disease with numerous manifestations and modes of presentation. Amongst the rarer aspects are: (1) familial incidence, (2) transient generalized lymphadenopathy, (3) involvement of the mucous membrane of the upper respiratory tract, and (4) involvement of the central nervous system (CNS). Detailed necropsy findings in cases of neurosarcoidosis have been re...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1974
ISSN: 0032-5473
DOI: 10.1136/pgmj.50.589.664